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Designing and generating custom transgenic models for your research!

Our Mission:

Transgenic models are vital tools in biomedical research. The CTM Basel is committed to supporting Uni Basel researchers by providing them with access to the latest transgenic and assisted reproduction technologies. Our service platform offers a wide variety of standard techniques while our own research focuses on devising novel gene delivery techniques while at the same time implementing the 3R principles for responsible animal experimentation.

Model Generation

Generation of sophisticated mouse models using the latest transgenic technologies

Support for Researchers

Assisting researchers in designing transgenic strategies and generating transgenic tools.

Optimized Colony Management

Optimizing mouse colony management through cryopreservation and assisted reproduction techniques.

Method Development

Development of novel transgenic tools and transgenic techniques.

Import, & Rederivation

Import and rederivation of mouse strains from external sources.

Our Services:

We offer a broad variety of services and support for the design, generation, preservation, and import of transgenic models:

IMPORTANT:

Before starting, all projects need to be
registered via our project database
Please do not send us any samples, material, or animals without prior agreement!
Contact us

Transgenic Model Design and Generation

Support for Transgenic Model Design

You need help with how to best design your model? We are there to support you with all steps of transgenic model design and generation!

DPI:
Design, Production & Injection

You have a complex project and little time at your hands? Our DPI project service provides the complete package – from microinjection to genotyping of offspring!

ROI:
Rapid Oocyte Injection

You have the capacity to genotype your offspring but need someone to perform microinjections or electroporations and transfers? Check out our ROI project service!

CHI:
ES-cell Chimera Generation

You need to inject embryonic stem (ES) cell clones into blastocysts? Check out our chimera generation service!

Assisted Reproduction & Cryopreservation

Are you looking for a way to preserve your strain, be it as a backup or to share it with others?

ECP:
Embryo Cryopreservation

ECP allows you to freeze down and safely store mouse embryos.

SCP:
Sperm Cryopreservation

SCP is a cost effective way of preserving mouse strains.

IVF:
In-vitro Fertilization

IVF allows the efficient production of embryos needed in other procedures.

Rederivation and Import of Mouse Strains

You want to study an existing mouse strain and need to rederive or import it? Let us support you for this process!

FEI:
Frozen Embryo Import

Frozen embryo import is an efficient way to introduce new mouse strains into the facility

FSI:
Frozen Sperm Import

Strain rederivation can be achieved using frozen sperm for in-vitro fertilization of wild type oocytes.

LSI:
Life Strain Import

Import of life strains is another, commonly chosen alternative for strain rederivation.

Project Database

The CTM’s custom project management database enables users to register their projects online. In addition, users are able to retrieve live updates for their projects and track ongoing CTM service activities.

You want to register a project at CTM?
Simply sign in to our project database to get started: